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Proceedings Paper

Speckle intensity correlation analysis as a method of tissue structure imaging
Author(s): Dmitry A. Zimnyakov; Kirill V. Larin; Alexey A. Mishin; Valery V. Tuchin
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Paper Abstract

Correlation analysis of the intensity fluctuations due to the laser light scattering is one of the prospective methods for tissue structure analysis and imaging. For steady- structure scattering media these fluctuations can be produced by laser beam scanning. Asymptotic behavior of the intensity autocorrelation and structure functions caused by small-scale peculiarities of the tissue scattering structure can be described with the usage of exponential factor. In our work this parameter is proposed as the visualization one for tissue structure imaging. Some experimental results obtained for human epidermis and sclera samples using this technique are discussed. Two-dimensional images of the healthy and diseased (psoriatic) human epidermis are presented. Computer simulation of the imaging reconstruction procedure had been carried out for different models of the scattered light intensity fluctuations. Presented results allow us to recommend similar methods (spatial speckle correlometry) as one of the methods for tissue structure monitoring.

Paper Details

Date Published: 11 December 1996
PDF: 12 pages
Proc. SPIE 2927, Optical and Imaging Techniques for Biomonitoring II, (11 December 1996); doi: 10.1117/12.260645
Show Author Affiliations
Dmitry A. Zimnyakov, Saratov State Univ. and Precision Mechanics and Control Institute (Russia)
Kirill V. Larin, Saratov State Univ. and Precision Mechanics and Contronl Institute (Russia)
Alexey A. Mishin, Precision Mechanics and Control Institute (Russia)
Valery V. Tuchin, Saratov State Univ. and Precision Mechanics and Control Institute (Russia)


Published in SPIE Proceedings Vol. 2927:
Optical and Imaging Techniques for Biomonitoring II
Hans-Jochen Foth; Renato Marchesini; Halina Podbielska M.D., Editor(s)

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