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Simulation of the non-thermal effects of strong field terahertz pulses on tumor cells
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Paper Abstract

Terahertz waves have potential of non-thermal regulation of cell physiological activities. Especially, the non-thermal effects of strong field terahertz pulses on the physical and chemical properties of cells and membrane structure need to be studied in detail. Therefore, this article uses the finite element method (FEM) to simulate and study the effects of strong field terahertz pulses on the cell membrane and nucleus membrane of cells. The simulation results show that both the single-frequency terahertz wave generated by CTFEL and wide-band terahertz pulses generated by lithium niobate crystal could cause a huge potential difference between cell membrane and nucleus membrane of the suspended spherical cell, which might lead to electroporation of the cell membrane or nucleus membrane.

Paper Details

Date Published: 9 September 2021
PDF: 6 pages
Proc. SPIE 11909, Tenth International Symposium on Ultrafast Phenomena and Terahertz Waves (ISUPTW 2021), 119090Y (9 September 2021);
Show Author Affiliations
Zhenzhen Ge, Univ. of Electronic Science and Technology of China (China)
Jun Zhou, Univ. of Electronic Science and Technology of China (China)
Shuting Wu, Univ. of Electronic Science and Technology of China (China)
Xin Rao, Hangzhou Dianzi Univ. (China)
Jiajia Qian, Univ. of Electronic Science and Technology of China (China)
Zheng Zhu, Univ. of Electronic Science and Technology of China (China)


Published in SPIE Proceedings Vol. 11909:
Tenth International Symposium on Ultrafast Phenomena and Terahertz Waves (ISUPTW 2021)
Liguo Zhu; Xiao Cheng; Daiming Ma, Editor(s)

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