Share Email Print

Proceedings Paper

Different sensitivity of cells from tumor-bearing organisms to continuous-wave and pulsed laser radiation (lambda = 632.8 nm) evaluated by chemiluminescence test
Author(s): Tiina I. Karu; T. P. Ryabykh; Sergei N. Antonov; Vladilen S. Letokhov
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Chemiluminescence test results were used to evaluate the sensitivity of human blood and murine splenocytes to continuous-wave (CW) and pulsed He-Ne laser light. It is demonstrated that CW radiation has in our experimental conditions practically no effect on the luminol-amplified chemiluminescence of four models under study. The pulsed radiation had a week inhibiting effect on the samples from healthy organisms but inhibited markedly the chemiluminescence of samples from tumor-bearing organisms. The effect depended on duration of dark period between pulses. A transient local heating mechanism is proposed to explain the inhibition of activity of NADPH-oxidase.

Paper Details

Date Published: 25 November 1996
PDF: 10 pages
Proc. SPIE 2929, Effects of Low-Power Light on Biological Systems II, (25 November 1996); doi: 10.1117/12.259981
Show Author Affiliations
Tiina I. Karu, Laser Technology Research Ctr. (Russia)
T. P. Ryabykh, Russian Cancer Research Ctr. (Russia)
Sergei N. Antonov, Institute of Radio Engineering and Electronics (Russia)
Vladilen S. Letokhov, Institute of Spectroscopy (Russia)

Published in SPIE Proceedings Vol. 2929:
Effects of Low-Power Light on Biological Systems II
Giulio Jori; Tiina I. Karu, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?