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Proceedings Paper

Fabrication and characterization of step-index biocompatible and biodegradable polyesters based optical fiber
Author(s): Agnieszka Gierej; Adam Filipkowski; Dariusz Pysz; Ryszard Buczyński; Maxime Vagenende; Sandra Van Vlierberghe; Peter Dubruel; Hugo Thienpont; Thomas Geernaert; Francis Berghmans
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Paper Abstract

Biocompatible optical waveguides receive increasing attention owing to their application potential in the biomedical field. Our focus is on the fabrication and characterization of a new step-index biodegradable polymer optical fiber (bioPOF) using two commercial polyesters: poly(D,L-lactic-co-glycolic acid) (PDLGA) and poly(D,L-lactic acid) (PDLLA). Both polymers are regulated by US FDA, which allows projecting future clinical use of fibers made from these materials. We manufactured three preforms and we subsequently drew optical fibers with a standard heat-draw tower. We describe the chemical properties of the materials throughout the whole production chain from polymer granulates to preforms and then to optical fibers. We look into to the influence of the processing on the molecular weight and thermal characteristics of the polymers. Our step-index bioPOF with an outer diameter of 1000 ± 50 μm and a core of around 570 ±30 μm features record low attenuation of 0.26 dB∕cm at 950 nm for step index bioPOF, and a numerical aperture of 0.163. Immersion in phosphate-buffered saline (PBS) leads to hydrolytic degradation of the bioPOFs over a period of 3 months, accompanied with a 91% molecular weight loss. From the degradation study results, we anticipate that our bioPOFs can be used for biophotonic applications requiring deep tissue light delivery, such as photodynamic therapy.

Paper Details

Date Published: 1 April 2020
PDF: 10 pages
Proc. SPIE 11355, Micro-Structured and Specialty Optical Fibres VI, 113550L (1 April 2020); doi: 10.1117/12.2556161
Show Author Affiliations
Agnieszka Gierej, Vrije Univ. Brussel (Belgium)
Adam Filipkowski, Institute of Electronic Materials Technology (Poland)
Dariusz Pysz, Institute of Electronic Materials Technology (Poland)
Ryszard Buczyński, Institute of Electronic Materials Technology (Poland)
Maxime Vagenende, Vrije Univ. Brussel (Belgium)
Univ. Gent (Belgium)
Sandra Van Vlierberghe, Univ. Gent (Belgium)
Peter Dubruel, Univ. Gent (Belgium)
Hugo Thienpont, Vrije Univ. Brussel (Belgium)
Thomas Geernaert, Vrije Univ. Brussel (Belgium)
Francis Berghmans, Vrije Univ. Brussel (Belgium)


Published in SPIE Proceedings Vol. 11355:
Micro-Structured and Specialty Optical Fibres VI
Kyriacos Kalli; Pavel Peterka; Christian-Alexander Bunge, Editor(s)

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