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Proceedings Paper

Optical noninvasive diagnostics of dynamic changes in the level of blood microcirculation and oxidative metabolism using temperature tests
Author(s): Elena V. Zharkikh; Yulia I. Loktionova; Galina I. Masalygina; Alexander I. Krupatkin; Victor V. Sidorov; Andrey V. Dunaev
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Paper Abstract

The problem of diabetes mellitus (DM) has attracted scientists of different specialities, as its prevalence is increasing worldwide and assumes the character of a pandemic. The use of optical non-invasive diagnostic methods is a promising direction for the early determination of the presence and severity of diabetic complications. This work is aimed at assessing changes in the uorescence intensity and the blood microcirculation level, evaluated in the skin of patients with DM with the use of local cold and heating tests. An experimental studies were carried out involving patients with type 2 DM and healthy controls. Significant differences were found in the changes in the level of microcirculation and oxidative metabolism under the in uence of local temperature effects (local heating and cooling) among patients and control group. The results can be used in further development of an optical non-invasive diagnosis of diabetes complications.

Paper Details

Date Published: 2 April 2020
PDF: 5 pages
Proc. SPIE 11363, Tissue Optics and Photonics, 1136321 (2 April 2020); doi: 10.1117/12.2555870
Show Author Affiliations
Elena V. Zharkikh, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Yulia I. Loktionova, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Galina I. Masalygina, Orel Regional Clinical Hospital (Russian Federation)
Alexander I. Krupatkin, National Medical Research Ctr. of Traumatology and Orthopedics (Russian Federation)
Victor V. Sidorov, SPE "LAZMA" (Russian Federation)
Andrey V. Dunaev, Orel State Univ. named after I.S. Turgenev (Russian Federation)

Published in SPIE Proceedings Vol. 11363:
Tissue Optics and Photonics
Valery V. Tuchin; Walter C. P. M. Blondel; Zeev Zalevsky, Editor(s)

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