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Proceedings Paper

Assessing corneal biomechanics without external excitation: heartbeat optical coherence elastography (Conference Presentation)
Author(s): Achuth Nair; Manmohan Singh; Salavat R. Aglyamov; Kirill V. Larin

Paper Abstract

Quantifying the biomechanical properties of the cornea is required for accurate assessment of tissue health. In this work, we evaluate cornea biomechanical properties during intraocular pressure fluctuation. This method results in a more physiologically relevant assessment of tissue mechanics, and thus diverges from typical elastography techniques that use externally induced deformation. Optical coherence elastography is used to detect displacements in the cornea as IOP is cycled during the heartbeat. The axial strains within the cornea are calculated from these displacements, so that dynamic changes in stiffness can be determined. The results indicate a gradient in axial strain within the cornea.

Paper Details

Date Published: 2 April 2020
Proc. SPIE 11363, Tissue Optics and Photonics, 113630O (2 April 2020); doi: 10.1117/12.2555000
Show Author Affiliations
Achuth Nair, Univ. of Houston (United States)
Manmohan Singh, Univ. of Houston (United States)
Salavat R. Aglyamov, Univ. of Houston (United States)
Kirill V. Larin, Univ. of Houston (United States)

Published in SPIE Proceedings Vol. 11363:
Tissue Optics and Photonics
Valery V. Tuchin; Walter C. P. M. Blondel; Zeev Zalevsky, Editor(s)

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