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Proceedings Paper

Spectropolarimetric comparison of molecular-genetic study of BRCA1 gene mutation types in patients with breast cancer and their relatives
Author(s): O. P. Peresunko; T. V. Kruk; K. M. Chala; S. B. Yermolenko; D. G. Gostyuk; Ion Gruia
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Paper Abstract

This work is devoted to the substantiation and selection of patients with breast cancer (BC) for the purpose of conducting expensive molecular genetic studies on genotyping. As diagnostic methods have been used ultraviolet spectrometry samples of blood plasma in the liquid state, infrared spectroscopy middle range (2,5 - 25 microns) dry residue of plasma polarization and laser diagnostic technique of thin histological sections of biological tissues. Obtained results showed that the use of spectrophotometry in the range of 1000-3000 cm-1 allowed to establish quantitative parameters of the plasma absorption rate of blood of patients in the third group in different ranges, which would allow in the future to conduct an express analysis of the patient's condition (procedure screening) for further molecular-genetic typing on BRCA I and II.

Paper Details

Date Published: 6 February 2020
PDF: 8 pages
Proc. SPIE 11369, Fourteenth International Conference on Correlation Optics, 1136925 (6 February 2020);
Show Author Affiliations
O. P. Peresunko, Bukovinian State Medical Univ. (Ukraine)
T. V. Kruk, Bukovinian State Medical Univ. (Ukraine)
K. M. Chala, Bukovinian State Medical Univ. (Ukraine)
S. B. Yermolenko, Chernivtsi National Univ. (Ukraine)
D. G. Gostyuk, Chernivtsi National Univ. (Ukraine)
Ion Gruia, Univ. din Bucuresti (Romania)

Published in SPIE Proceedings Vol. 11369:
Fourteenth International Conference on Correlation Optics
Oleg V. Angelsky, Editor(s)

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