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Proceedings Paper

High-resolution tissue imaging using moxifloxacin as a clinically compatible cell labeling agent (Conference Presentation)

Paper Abstract

High-resolution fluorescence imaging using moxifloxacin as a clinically compatible cell labeling agent is described. Moxifloxacin is an antibiotic with good pharmacokinetic properties for tissue penetration and it has intrinsic fluorescence under ultraviolet (UV) excitation. Alternative usage of moxifloxacin as the cell labeling agent was demonstrated in two-photon tissue imaging of various tissues. Cells within tissues were visualized in enhanced contrasts with moxifloxacin. Moxifloxacin based tissue imaging was explored not only in two-photon excitation but also in both single-photon and three-photon excitations. Moxifloxacin based fluorescence imaging is clinically compatible and has potentials for clinical applications where the cellular examination is needed.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11244, Multiphoton Microscopy in the Biomedical Sciences XX, 112441P (9 March 2020);
Show Author Affiliations
Ki Hean Kim, Pohang Univ. of Science and Technology (Korea, Republic of)
Seunghun Lee, Pohang Univ. of Science and Technology (Korea, Republic of)
Bumju Kim, Pohang Univ. of Science and Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 11244:
Multiphoton Microscopy in the Biomedical Sciences XX
Ammasi Periasamy; Peter T. C. So; Karsten König, Editor(s)

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