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Proceedings Paper

A novel gravity valve and its application in a 3D printed centrifugal fluidic-system for solid phase extraction (SPE)
Author(s): Yong Zhang; Jiwen Xiang; Yunxia Wang; Zheng Qiao; Wanjun Wang
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Paper Abstract

A 3D centrifugal cartridge with gravity valve, capillary valves, and Coriolis switching valve was designed, fabricated, and tested for Solid Phase Extraction (SPE). In particular, the novel three-dimensional gravity valve helps to release reagents in not-sequentially increased rotation speeds. The sequential control of these valves was simply achieved by manipulating the rotating direction and speed of the cartridge. The prototype microfluidic cartridge was 3D printed with a FDM printer and experimentally tested. Anthracene, which was one of the Polycyclic Aromatic Hydrocarbons (PAHs), was used as the target analyte and tested. C18 was used as the stationary sorbent and fluorescence method was adopted to detect anthracene. The concentrations of the anthracene testing samples were 1μg/L (1ppb), 5μg/L, and 10μg/L (anthracene/water), respectively. The volumes of testing sample and eluent (nonane) were 10mL and 1mL respectively. Experiments showed that 7 times of enrichment of the original samples were achieved. This centrifugal SPE system could be potentially used as a portable on-situ pollutant enrichment and detection device.

Paper Details

Date Published: 25 February 2020
PDF: 6 pages
Proc. SPIE 11235, Microfluidics, BioMEMS, and Medical Microsystems XVIII, 112350I (25 February 2020); doi: 10.1117/12.2550845
Show Author Affiliations
Yong Zhang, Louisiana State Univ. (United States)
Jiwen Xiang, Louisiana State Univ. (United States)
Yunxia Wang, Louisiana State Univ. (United States)
Zheng Qiao, Louisiana State Univ. (United States)
Wanjun Wang, Louisiana State Univ. (United States)

Published in SPIE Proceedings Vol. 11235:
Microfluidics, BioMEMS, and Medical Microsystems XVIII
Bonnie L. Gray; Holger Becker, Editor(s)

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