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Proceedings Paper

Compact microLED optrode device for patterned inter-cortical optogenetics (Conference Presentation)
Author(s): Niall McAlinden; Yunzhou Cheng; Robert Scharf; Enyuan Xie; Erdan Gu; Rohit Sharma; Prashant Tathireddy; Christopher F. Reiche; Martin D. Dawson; Loren Rieth; Steve Blair; Keith Mathieson

Paper Abstract

There is current demand for pattern programmable devices that can deliver light to deep brain structures for use in optogenetic experiments. Here we introduce a microLED optrode device with 181 individually addressable sites, each with the capability to optogenetically excite thousands of neurons in vivo. The device consists of a 10 x 10 glass microneedle array directly integrated with a custom fabricated microLED device. 100 microLEDs couple to the needle tips for intra-cortical light delivery and 81 microLEDs sit at interstitial points for surface illumination. Light delivery and thermal properties are comprehensively evaluated.

Paper Details

Date Published: 9 March 2020
PDF
Proc. SPIE 11226, Neural Imaging and Sensing 2020, 112261D (9 March 2020); doi: 10.1117/12.2550809
Show Author Affiliations
Niall McAlinden, Univ. of Strathclyde (United Kingdom)
Yunzhou Cheng, Univ. of Strathclyde (United Kingdom)
Robert Scharf, The Univ. of Utah (United States)
Enyuan Xie, Univ. of Strathclyde (United Kingdom)
Erdan Gu, Univ. of Strathclyde (United Kingdom)
Rohit Sharma, The Univ. of Utah (United States)
Prashant Tathireddy, The Univ. of Utah (United States)
Christopher F. Reiche, The Univ. of Utah (United States)
Martin D. Dawson, Univ. of Strathclyde (United Kingdom)
Loren Rieth, The Feinstein Institute for Medical Research (United States)
Steve Blair, The Univ. of Utah (United States)
Keith Mathieson, Univ. of Strathclyde (United Kingdom)


Published in SPIE Proceedings Vol. 11226:
Neural Imaging and Sensing 2020
Qingming Luo; Jun Ding; Ling Fu, Editor(s)

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