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Proceedings Paper

Wavelet-based protoacoustic signal denoising for proton range verification
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Paper Abstract

Protoacoustics, the measurement of the pressure waves emitted by thermal expansion resulting from proton dose deposition, may be used to obtain the depth of the Bragg-peak (BP) by measuring the time-of-flight of the pressure wave. However, using the method in the clinic has a drawback since numerous measured signals were averaged to identify the accurate signal peak from the indistinguishable noises. We proposed a wavelet-based denoising method to significantly reduce noise in collected protoacoustic signals and improve the BP identification accuracy with fewer signal averages. The average 1024 signal, which has been used in the published study, was used as the reference to identify the accurate acoustic location. We used Daubechies (db) 4 wavelet transform to decompose the collected signals to recover the useful protoacoustic signals. Our approach was able to identify the BP signal up to the average 8 signals that correspond to the dose (<1.5 Gy). This denoising technique would be useful for future 2D/3D protoacoustic imaging and make protoacoustic clinically useful for proton range verification.

Paper Details

Date Published: 16 March 2020
PDF: 6 pages
Proc. SPIE 11319, Medical Imaging 2020: Ultrasonic Imaging and Tomography, 1131904 (16 March 2020); doi: 10.1117/12.2550768
Show Author Affiliations
James Sohn, Winship Cancer Institute of Emory Univ. (United States)
Wei Nie, Univ. of Nebraska at Omaha (United States)
Stephen M. Avery, Univ. of Pennsylvania (United States)
Xiuxiu He, Emory Univ. (United States)
Jun Zhou, Winship Cancer Institute of Emory Univ. (United States)
Xiaofeng Yang, Winship Cancer Institute of Emory Univ. (United States)
Tian Liu, Winship Cancer Institute of Emory Univ. (United States)

Published in SPIE Proceedings Vol. 11319:
Medical Imaging 2020: Ultrasonic Imaging and Tomography
Brett C. Byram; Nicole V. Ruiter, Editor(s)

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