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Proceedings Paper

Automatic epicardial fat segmentation in cardiac CT imaging using 3D deep attention U-Net
Author(s): Xiuxiu He; Bang Jun Guo; Yang Lei; Tonghe Wang; Tian Liu; Walter J. Curran; Long Jiang Zhang; Xiaofeng Yang
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Paper Abstract

Epicardial fat is a visceral fat deposit, located between the heart and the pericardium, which shares many of the pathophysiological properties of other visceral fat deposits, it may also potentially cause local inflammation and likely has direct effects on coronary atherosclerosis. epicardial fat is also associated with other known factors, such as obesity, diabetes mellitus, age, and hypertension, which interprets its role as an independent risk marker intricate. For the investigation of the relationship between epicardial fat and various diseases, it is important to segment the epicardial fat in a fast and reproducible way. However, epicardial fat has a variable distribution, and multiple conditions may affect the volume of the EF, which can increase the complexity of the already time-consuming manual segmentation work. In this study, we propose to use a 3D deep attention U-Net method to segment the epicardial fat for cardiac CT image automatically. To test the proposed method, we applied it to 40 patients’ cardiac CT images. Five-fold cross-validation experiments were used to evaluate the proposed method. We calculated the Dice similarity coefficient (DSC), precision, and recall (MSD) indices between the ground truth and our segmentation to quantify the segmentation accuracy of the proposed method. Overall, the DSC, precision, and recall were 85% ± 5%, 86% ± 4%, and 89% ± 5%, which demonstrated the detection and segmentation accuracy of the proposed method.

Paper Details

Date Published: 10 March 2020
PDF: 7 pages
Proc. SPIE 11313, Medical Imaging 2020: Image Processing, 113132D (10 March 2020); doi: 10.1117/12.2550383
Show Author Affiliations
Xiuxiu He, Emory Univ. (United States)
Bang Jun Guo, Emory Univ. (United States)
Southern Medical Univ. (China)
Medical School of Nanjing Univ. (China)
Yang Lei, Emory Univ. (United States)
Tonghe Wang, Emory Univ. (United States)
Tian Liu, Emory Univ. (United States)
Walter J. Curran, Emory Univ. (United States)
Long Jiang Zhang, Southern Medical Univ. (China)
Medical School of Nanjing Univ. (China)
Xiaofeng Yang, Emory Univ. (United States)

Published in SPIE Proceedings Vol. 11313:
Medical Imaging 2020: Image Processing
Ivana Išgum; Bennett A. Landman, Editor(s)

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