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Proceedings Paper

Prior knowledge driven machine learning approach for PET sinogram data denoising
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Paper Abstract

Machine learning, especially convolutional neural network (CNN) approach has been successfully applied in noise suppression in natural image. However, shifting from natural image to medical image filed remains challenging due to specific difficulties such as training samples limitation, clinically meaningful image quality requirement and so on. To address this challenge, one possible solution is to incorporate our human prior knowledge into the machine learning model to better benefit its power. Therefore, in this work, we propose one prior knowledge driven machine learning based approach for positron emission tomography (PET) sinogram data denoising. Two main properties of PET sinogram data were considered in CNN architecture design, which are the Poisson statistics of the data and different correlation strength in the detector and view directions. Specially, for the statistical property, the sparse non-local method was used. For the correlation property, separate convolution was applied in two directions respectively. Experimental results showed the proposed model outperform the CNN model without prior knowledge. Results also demonstrate our insight of applying human knowledge strength the power of machine learning in medical imaging field.

Paper Details

Date Published: 16 March 2020
PDF: 5 pages
Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 113124A (16 March 2020); doi: 10.1117/12.2549900
Show Author Affiliations
Siming Lu, State Univ. of New York (United States)
Jiaxing Tan, State Univ. of New York (United States)
Yongfeng Gao, State Univ. of New York (United States)
Yongyi Shi, State Univ. of New York (United States)
Zhengrong Liang, State Univ. of New York (United States)

Published in SPIE Proceedings Vol. 11312:
Medical Imaging 2020: Physics of Medical Imaging
Guang-Hong Chen; Hilde Bosmans, Editor(s)

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