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Proceedings Paper

Impact of photon counting detector spectral distortion on virtual non-contrast CT imaging
Author(s): Mang Feng; Xu Ji; Ran Zhang; Jessica R. Miller; Guang-Hong Chen; Ke Li
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Paper Abstract

Virtual non-contrast (VNC) CT images derived from multi-energy CT data have demonstrated many valuable clinical applications. However, VNC CT has not yet established itself as a technology that can reliably replace the true non-contrast CT. One commonly observed phenomenon is an erroneous removal or reduction of calcium signal in VNC images. The purpose of this work is to develop a photon counting CT-based method to decouple the iodine signal from the calcium signal to achieve VNC CT imaging. Thanks to the energy resolving capability of the photon counting detector (PCD), a photon counting CT enables all single kV CT data to carry additional spectral information needed for VNC CT reconstruction. However, the energy discriminating capability of a real PCD system is far from ideal, which can severely degrade the fidelity of the encoded spectral information and the efficiency of the material decomposition. In this work, a physics-based model of the PCD energy response function was developed and experimentally validated. By leveraging this model, a method was developed to correct the distorted spectral information in the measured PCD energy bin data, allowing the true post image object spectrum to be estimated to accomplish accurate three-material decomposition and VNC CT reconstruction. Both numerical simulation and experimental results demonstrated that the proposed spectral distortion correction method can effectively improve the CT number accuracy of both iodine-containing vessels and calcium-containing bony structures in VNC CT images.

Paper Details

Date Published: 16 March 2020
PDF: 6 pages
Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 113121J (16 March 2020); doi: 10.1117/12.2549737
Show Author Affiliations
Mang Feng, Univ. of Wisconsin-Madison (United States)
Xu Ji, Univ. of Wisconsin-Madison (United States)
Ran Zhang, Univ. of Wisconsin-Madison (United States)
Jessica R. Miller, Univ. of Wisconsin-Madison (United States)
Guang-Hong Chen, Univ. of Wisconsin-Madison (United States)
Ke Li, Univ. of Wisconsin-Madison (United States)


Published in SPIE Proceedings Vol. 11312:
Medical Imaging 2020: Physics of Medical Imaging
Guang-Hong Chen; Hilde Bosmans, Editor(s)

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