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Two photon luminescence of gold nanorods with breast cancer cells
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Paper Abstract

Gold nanorods have special optical properties, good biological compatibility and easy preparation, making them have broad application prospects in drug carriers and medical imaging. In this paper, the two photon luminescence of silica modified gold nanorods incubated with different subtypes of breast cancer cells was observed. We demonstrate the effects of different subtypes breast cancer cells on cellular uptake of gold nanorods. And The results show that significant decreases internalization of gold nanorods with the presence of fetal bovine serum protein in cell culture. Two-photon imaging revealed that cellular uptake of gold nanorods was affected by serum and subtypes of cells, and movement of gold nanorods in the cells was observed. Our findings can provide useful information for medical imaging of gold nanorods in biomedical application.

Paper Details

Date Published: 20 December 2019
PDF: 6 pages
Proc. SPIE 11209, Eleventh International Conference on Information Optics and Photonics (CIOP 2019), 1120945 (20 December 2019); doi: 10.1117/12.2549452
Show Author Affiliations
Xiang Sang, Fujian Normal Univ. (China)
Kexin Wang, Fujian Normal Univ. (China)
Shuanghuang Xiao, Fujian Normal Univ. (China)
Hongqin Yang, Fujian Normal Univ. (China)
Yiru Peng, Fujian Normal Univ. (China)
Shusen Xie, Fujian Normal Univ. (China)
Jianling Chen, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 11209:
Eleventh International Conference on Information Optics and Photonics (CIOP 2019)
Hannan Wang, Editor(s)

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