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Proceedings Paper

Improved functional imaging of ganglion neuronal and photoreceptor cell layers in living human retina (Conference Presentation)
Author(s): Gereon M. Hüttmann; Clara Pfäffle; Hendrik Spahr; Lisa Kutzner; Sazan Burhan; Felix Hilge; Yoko Miura; Dierck Hillmann

Paper Abstract

Non-invasive functional retinal imaging in humans is of tremendous interest. By using phase-sensitive full-field swept-source OCT (FF-SS-OCT) we demonstrated simultaneous quantitative imaging of the optical activation in the photoreceptor and ganglion/inner plexiform layer. Since the signals from the ganglion cells layer are ten-fold smaller than those from the photoreceptor cells a new algorithms for suppression of motion artifacts and pulsatile blood flow in the retinal vessels is important. With improved data evaluation we simultaneously measured the activation of photoreceptors and ganglion/inner plexiform with high quality and were able to analyze the spatial and temporal response of cells in the ganglion/inner plexiform over more than 10 seconds.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280F (9 March 2020); doi: 10.1117/12.2549083
Show Author Affiliations
Gereon M. Hüttmann, Univ. zu Lübeck (Germany)
Clara Pfäffle, Univ. zu Lübeck (Germany)
Hendrik Spahr, Univ. zu Lübeck (Germany)
Lisa Kutzner, Univ. zu Lübeck (Germany)
Sazan Burhan, Univ. zu Lübeck (Germany)
Felix Hilge, Univ. zu Lübeck (Germany)
Yoko Miura, Univ. zu Lübeck (Germany)
Dierck Hillmann, Thorlabs GmbH (Germany)

Published in SPIE Proceedings Vol. 11228:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV
Joseph A. Izatt; James G. Fujimoto, Editor(s)

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