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Proceedings Paper

Radiomics and artificial intelligence analysis of CT data for the identification of prognostic features in multiple myeloma
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Paper Abstract

Multiple Myeloma (MM) is a blood cancer implying bone marrow involvement, renal damages and osteolytic lesions. The skeleton involvement of MM is at the core of the present paper, exploiting radiomics and artificial intelligence to identify image-based biomarkers for MM. Preliminary results show that MM is associated to an extension of the intrabone volume for the whole body and that machine learning can identify CT image features mostly correlating with the disease evolution. This computational approach allows an automatic stratification of MM patients relying of these biomarkers and the formulation of a prognostic procedure for determining the disease follow-up.

Paper Details

Date Published: 16 March 2020
PDF: 7 pages
Proc. SPIE 11314, Medical Imaging 2020: Computer-Aided Diagnosis, 113144A (16 March 2020); doi: 10.1117/12.2548983
Show Author Affiliations
Daniela Schenone, Univ. degli Studi di Genova (Italy)
Rita Lai, Univ. degli Studi di Genova (Italy)
Michele Cea, Univ. degli Studi di Genova (Italy)
Federica Rossi, Univ. degli Studi di Genova (Italy)
Lorenzo Torri, Univ. degli Studi di Genova (Italy)
Bianca Bignotti, Univ. degli Studi di Genova (Italy)
IRCCS Ospedale Policlinico San Martino (Italy)
Giulia Succio, IRCCS Ospedale Policlinico San Martino (Italy)
Stefano Gualco, Univ. degli Studi di Genova (Italy)
Alessio Conte, Univ. degli Studi di Genova (Italy)
Alida Dominietto, IRCCS Ospedale Policlinico San Martino (Italy)
Anna Maria Massone, Univ. degli Studi di Genova (Italy)
CNR-SPIN (Italy)
Michele Piana, Univ. degli Studi di Genova (Italy)
CNR-SPIN (Italy)
Cristina Campi, Univ. di Padova (Italy)
Francesco Frassoni, Univ. degli Studi di Genova (Italy)
Gianmario Sambuceti, Univ. degli Studi di Genova (Italy)
IRCCS Ospedale Policlinico San Martino (Italy)
Alberto Stefano Tagliafico, Univ. degli Studi di Genova (Italy)
IRCCS Ospedale Policlinico San Martino (Italy)


Published in SPIE Proceedings Vol. 11314:
Medical Imaging 2020: Computer-Aided Diagnosis
Horst K. Hahn; Maciej A. Mazurowski, Editor(s)

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