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Proceedings Paper

In-vivo imaging of neurological signatures using coherent optical techniques (Conference Presentation)
Author(s): David W. Blodgett; Carissa Rodriguez; Eyal Bar-Kochba; Clara Scholl; Nicole Steiner; Austen Lefebvre; Marek Mirski

Paper Abstract

Optical neuroimaging technologies aim to observe neural tissue structure and function by detecting changes in optical signals (scatter, absorption, etc…) that accompany a range of anatomical and functional properties of brain tissue. At present, there is a tradeoff between spatial and temporal resolution that is not currently optimized in a single imaging modality. We have developed a coherent optical imaging approach that begins to remove this trade-off and have demonstrated high spatiotemporal (<100µm and >100Hz) in-vivo recordings of neural activity over large 20mm2 areas.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11226, Neural Imaging and Sensing 2020, 112260S (9 March 2020); doi: 10.1117/12.2548582
Show Author Affiliations
David W. Blodgett, Johns Hopkins Univ. Applied Physics Lab., LLC (United States)
Carissa Rodriguez, Johns Hopkins Univ. Applied Physics Lab., LLC (United States)
Eyal Bar-Kochba, Johns Hopkins Univ. Applied Physics Lab., LLC (United States)
Clara Scholl, Johns Hopkins Univ. Applied Physics Lab., LLC (United States)
Nicole Steiner, Johns Hopkins Univ. Applied Physics Lab., LLC (United States)
Austen Lefebvre, The Johns Hopkins Univ. School of Medicine (United States)
Marek Mirski, The Johns Hopkins Univ. School of Medicine (United States)


Published in SPIE Proceedings Vol. 11226:
Neural Imaging and Sensing 2020
Qingming Luo; Jun Ding; Ling Fu, Editor(s)

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