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Proceedings Paper

Characterizing the elasticity of thin silk biomaterials using quantitative micro-elastography (Conference Presentation)
Author(s): Matt Hepburn; Filippo Valente; Phillip Wijesinghe; Rodney J. Dilley; Brendan F. Kennedy

Paper Abstract

Silk graft biomaterials are proposed to improve the surgical repair of ruptured eardrums. The correct mechanical properties of these silk membranes are critical to ensure optimum patient outcomes. In this study, we use quantitative micro-elastography to characterize the elasticity of three dimensionally printed silk membrane scaffolds. To achieve this, we present a novel sample preparation technique that improves image quality. Using this approach we are able to characterize changes in silk membrane elasticity and study microscale elasticity gradients. We believe this approach will become an important tool to image biomaterials previously thought to be unsuitable for optical elastography.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 1124206 (9 March 2020); doi: 10.1117/12.2548513
Show Author Affiliations
Matt Hepburn, Harry Perkins Institute of Medical Research (Australia)
Filippo Valente, Ear Science Institute Australia (Australia)
Phillip Wijesinghe, Univ. of St. Andrews (United Kingdom)
Rodney J. Dilley, Ear Science Institute Australia (Australia)
Brendan F. Kennedy, Harry Perkins Institute of Medical Research (Australia)


Published in SPIE Proceedings Vol. 11242:
Optical Elastography and Tissue Biomechanics VII
Kirill V. Larin; Giuliano Scarcelli, Editor(s)

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