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Proceedings Paper

Core/Shell Iron Oxide@Gold nanoparticles for dual-modal CT/MRI imaging
Author(s): Oshra Betzer; Menachem Motiei; Tamar Dreifuss; Tamar Sadan; Noam Omer; Tamar Blumenfeld-Katzir; Zhuang Liu; Noam Ben-Eliezer; Rachela Popovtzer
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Paper Abstract

Multimodal imaging, integrating different imaging modalities, is emerging as a promising strategy for improving both preclinical and clinical imaging. Computed tomography (CT) and magnetic resonance imaging (MRI) are among the widely clinically-used imaging techniques. These imaging modalities are used for disease diagnosis and screening, each providing different and complementary information about the patient and the disease state. Nanoparticles are considered promising contrast agents for in vivo imaging applications, providing improved imaging and targeting capabilities compared to the commonly used contrast compounds. In this project, we present the development of a novel hybrid nanostructure, comprising of iron oxide core and gold shell nanoparticle for dual model CT and MRI imaging. The hybrid structures presented herein have potential to serve as a unique platform for precision imaging.

Paper Details

Date Published: 21 February 2020
PDF: 9 pages
Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 112541F (21 February 2020); doi: 10.1117/12.2548430
Show Author Affiliations
Oshra Betzer, Bar-Ilan Univ. (Israel)
Soochow Univ. (China)
Menachem Motiei, Bar-Ilan Univ. (Israel)
Tamar Dreifuss, Bar-Ilan Univ. (Israel)
Tamar Sadan, Bar-Ilan Univ. (Israel)
Noam Omer, Tel Aviv Univ. (Israel)
Tamar Blumenfeld-Katzir, Tel Aviv Univ. (Israel)
Zhuang Liu, Soochow Univ. (China)
Noam Ben-Eliezer, Tel Aviv Univ. (Israel)
Rachela Popovtzer, Bar-Ilan Univ. (Israel)

Published in SPIE Proceedings Vol. 11254:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII
Dror Fixler; Ewa M. Goldys, Editor(s)

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