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Proceedings Paper

Uptake study of gold nanoparticles into cancer cells using high-order image correlation spectroscopy
Author(s): D. Katoozi; A. H. A. Clayton; D. J. Moss; J. W. M. Chon
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Paper Abstract

Gold nanoparticles (AuNPs), due to unique optical properties and has become excellent tools for cancer diagnosis and therapy. Various techniques are used to get information about AuNPs cellar uptake and aggregation, however; these methods are not suitable for live cell imaging. Here we used non-destructive characterisation method namely High order Image Correlation Spectroscopy (HICS) combined with Dark Field Microscopy (DFM) is used to get information about cellular uptake and aggregation of 80 nm gold nanosphere (AuNSs) inside HeLa cell. Results confirm the accuracy and simple nature of the proposed method for future live-cell imaging.

Paper Details

Date Published: 31 December 2019
PDF: 7 pages
Proc. SPIE 11201, SPIE Micro + Nano Materials, Devices, and Applications 2019, 112011Y (31 December 2019); doi: 10.1117/12.2547985
Show Author Affiliations
D. Katoozi, Swinburne Univ. of Technology (Australia)
A. H. A. Clayton, Swinburne Univ. of Technology (Australia)
D. J. Moss, Swinburne Univ. of Technology (Australia)
J. W. M. Chon, Swinburne Univ. of Technology (Australia)

Published in SPIE Proceedings Vol. 11201:
SPIE Micro + Nano Materials, Devices, and Applications 2019
M. Cather Simpson; Saulius Juodkazis, Editor(s)

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