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Dendrimer phthalocyanine based nanoparticles: an effective photosensitizer for enhanced photodynamic therapy
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Paper Abstract

A novel polymeric nanoparticle was developed between the negatively charged dendrimer phthalocyanine and positively triblock copolymer for the use as an effective photosensitizer in photodynamic therapy. The intracellular uptake of dendrimer phthalocyanines in HeLa cell was significantly enhanced by encapsulated into nanoparticles. The photocytotoxicity of dendrimer phthalocyanines incorporated into polymeric micelles was also increased. The presence of nanoparticles located induced efficient cell death.

Paper Details

Date Published: 20 December 2019
PDF: 6 pages
Proc. SPIE 11209, Eleventh International Conference on Information Optics and Photonics (CIOP 2019), 1120923 (20 December 2019); doi: 10.1117/12.2547956
Show Author Affiliations
Kuizhi Chen, Fujian Normal Univ. (China)
Ruotao Guo, Fujian Normal Univ. (China)
Shuanghuang Xiao, Fujian Normal Univ. (China)
Xia Li, Fujian Normal Univ. (China)
Jiao Wang, Fujian Normal Univ. (China)
Yiru Peng, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 11209:
Eleventh International Conference on Information Optics and Photonics (CIOP 2019)
Hannan Wang, Editor(s)

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