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Proceedings Paper

Smartphone-based measurement of serum phosphate levels for patients with kidney disease (Conference Presentation)

Paper Abstract

Monitoring serum phosphate level is critical for patients with kidney disease and those undergoing dialysis. We report a POC serum phosphate measurement device, by integrating a disposable paper-based microfluidic chip with a smartphone-based measurement system. The inexpensive microfluidic chip collects a droplet of blood from the patient and isolates the serum, which then reacts with a malachite green reagent, resulting in a colorimetric change, measured using a smartphone-based device. This POC instrument was tested on clinical samples obtained from patients undergoing dialysis, and we observed a strong statistical correlation between our results and the tests performed in a clinical laboratory.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11230, Optics and Biophotonics in Low-Resource Settings VI, 1123009 (9 March 2020); doi: 10.1117/12.2547901
Show Author Affiliations
Aniruddha Ray, The Univ. of Toledo (United States)
Sarah Esparza, Univ. of California, Los Angeles (United States)
Dimei Wu, Univ. of California, Los Angeles (United States)
Mark Hanudel, Univ. of California, Los Angeles (United States)
Hyou-Arm Joung, Univ. of California, Los Angeles (United States)
Barbara Gales, Univ. of California, Los Angeles (United States)
Isidro Salusky, Univ. of California, Los Angeles (United States)
Aydogan Ozcan, Univ. of California, Los Angeles (United States)


Published in SPIE Proceedings Vol. 11230:
Optics and Biophotonics in Low-Resource Settings VI
David Levitz; Aydogan Ozcan, Editor(s)

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