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Proceedings Paper

Optical methods for non-invasive assessment of arteriole flow impedance (Conference Presentation)

Paper Abstract

Vascular impedance is a frequency dependent quantity relating a vascular compartment's flow dynamics to pressure changes. Although vascular impedance has been investigated in larger arteries, probing smaller arterioles using similar techniques has been difficult due to their small cross-sectional area. Here we show how vascular impedance can be quantified based on pulsatile data from cerebral measurements using diffuse correlation spectroscopy (DCS) as well as near-infrared spectroscopy (NIRS). Results from head of bed tilting in healthy volunteers will be presented, showing that quantification of vascular impedance is possible. Applications and the relationship to cerebral autoregulation will be discussed.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11226, Neural Imaging and Sensing 2020, 1122610 (9 March 2020); doi: 10.1117/12.2547639
Show Author Affiliations
Jason Yang, Carnegie Mellon Univ. (United States)
Alexander Ruesch, Carnegie Mellon Univ. (United States)
Jana Kainerstorfer, Carnegie Mellon Univ. (United States)


Published in SPIE Proceedings Vol. 11226:
Neural Imaging and Sensing 2020
Qingming Luo; Jun Ding; Ling Fu, Editor(s)

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