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Proceedings Paper

Optimized detector angle for improving signal-to-noise ratio of pinhole x-ray fluorescence computed tomography
Author(s): Jing Guo; Peng Feng; Luzhen Deng; Yan Luo; Peng He
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Paper Abstract

In this work, we studied how the detector angle affects the signal-to-noise ratio (S/N) of X-ray fluorescence CT (XFCT), which is a major factor in reducing background noise and improving the detection sensitivity. We simulated a benchtop multi-pinhole XFCT system including a fan-beam x-ray source, a phantom (2.5 cm in diameter) consisting of one insert with gold nanoparticles (GNPs) , 2-sided multi-pinhole (3 pinholes) collimator aimed to acquire multiple projections simultaneously and 2-sided two-dimensional (2D) detector based on Geant4. The signal and noise were defined as the emitted Kα1=68.8keV X-ray fluorescence and Compton scatter fluorescence, respectively. The result was evaluated in three approaches at four different detector angles 60° (forward-scatter), 90° (side-scatter), 120° and 150° (back-scatter). In the simulation, the tube voltage was set to 90,100,110 and 120keV with fixed GNPs concentration (2%) and insert diameter (6mm).Then, the GNPs concentration was increased from 0.25%, 0.5%, 1% to 2% with fixed tube voltage (120keV) and insert diameter (6mm). Next, the insert diameter was set to 4, 6, 8, and 10mm with fixed tube voltage (120keV) and GNPs concentration (1%). The optimized detection angle was acquired by comparing the correlation between S/N and detector angles in terms of tube voltage, GNPs concentration and insert diameter. The experimental results demonstrated that, for most circumstances, the highest S/N could be obtained when detector angle was set to 120°.

Paper Details

Date Published: 20 December 2019
PDF: 4 pages
Proc. SPIE 11209, Eleventh International Conference on Information Optics and Photonics (CIOP 2019), 112091O (20 December 2019); doi: 10.1117/12.2547561
Show Author Affiliations
Jing Guo, Chongqing Univ. (China)
Peng Feng, Chongqing Univ. (China)
Luzhen Deng, Chongqing Univ. (China)
Yan Luo, Chongqing Univ. (China)
Peng He, Chongqing Univ. (China)

Published in SPIE Proceedings Vol. 11209:
Eleventh International Conference on Information Optics and Photonics (CIOP 2019)
Hannan Wang, Editor(s)

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