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Proceedings Paper

Holistic quantification of cutaneous microcirculation with spatial frequency domain imaging (SFDI) and coherent hemodynamics spectroscopy (CHS) based on a dynamic microcirculation PIPE model (Conference Presentation)
Author(s): Min Xu; Yang Zheng; Xinlin Chen; Weihao Lin; Bixin Zeng

Paper Abstract

We report holistic quantification of cutaneous microcirculation with spatial frequency domain imaging (SFDI) and coherent hemodynamics spectroscopy (CHS) based on a dynamic microcirculation PIPE model. A simple device was developed to induce periodic variations in cutaneous blood volume and flow velocity. Both baseline and dynamic features of cutaneous microcirculation for healthy subjects were completely quantified. The CHS findings were further related to SSMD-SFDI imaging of the same healthy subjects under reactive hyperemia protocol. The results demonstrate spatial frequency domain imaging and coherent hemodynamics spectroscopy based on the dynamic microcirculation PIPE model provides a valuable tool for functional studies with hemodynamic-based techniques.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 112390K (9 March 2020); doi: 10.1117/12.2547547
Show Author Affiliations
Min Xu, The City Univ. of New York (United States)
Yang Zheng, Wenzhou Medical Univ. (China)
Xinlin Chen, Wenzhou Medical Univ. (China)
Weihao Lin, Wenzhou Medical Univ. (China)
Bixin Zeng, Wenzhou Medical Univ. (China)


Published in SPIE Proceedings Vol. 11239:
Dynamics and Fluctuations in Biomedical Photonics XVII
Valery V. Tuchin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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