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Proceedings Paper

Distinct targets for blue light photoinactivation (Conference Presentation)
Author(s): Carolina dos Anjos; Fabio C. Pogliani; Fábio P. Sellera; Maurício Baptista; Martha S. Ribeiro; Nilton Lincopan; Milena Dropa; Caetano Sabino

Paper Abstract

Our aim was to evaluate membrane integrity and the occurrence of possible DNA damage caused by blue light inactivation. We used in our study three bacterial pathogens with distinct biochemical and morphological characteristics: Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Through electrophoresis and fluorescence spectroscopy analysis we observed distinct molecular damage between the evaluated microorganisms. Thus, our results suggest distinct mechanisms of inactivation by light blue among different pathogen species. Individual biochemical characteristics of each microorganism may be responsible for the occurrence of distinct structural damage

Paper Details

Date Published: 10 March 2020
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Proc. SPIE 11223, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2020, 112230O (10 March 2020);
Show Author Affiliations
Carolina dos Anjos, Univ. de São Paulo (Brazil)
Fabio C. Pogliani, Univ. de São Paulo (Brazil)
Fábio P. Sellera, Univ. de São Paulo (Brazil)
Maurício Baptista, Univ. de São Paulo (Brazil)
Martha S. Ribeiro, Univ. de São Paulo (Brazil)
Nilton Lincopan, Univ. de São Paulo (Brazil)
Milena Dropa, Univ. de São Paulo (Brazil)
Caetano Sabino, Univ. de São Paulo (Brazil)


Published in SPIE Proceedings Vol. 11223:
Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2020
Tianhong Dai; Jürgen Popp; Mei X. Wu M.D., Editor(s)

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