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Proceedings Paper

Application of over-sampling nano-sensitive optical coherence tomography for monitoring corneal internal structural changes in corneal cross-linking
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Paper Abstract

Corneal cross-linking (CXL) has grown from an interesting concept to a practical clinical treatment for corneal ectatic disease globally in the past three decades. In both understanding the principle of how CXL proceeds and monitoring the clinical procedure, detection of structural changes during cornea CXL plays a significant role. This paper demonstrates a novel over-sampling nano-sensitive optical coherence tomography (osnsOCT) method, which is potential to detect nanoscale structural changes in various tissues, to simultaneously measure the structural variations during the corneal CXL treatment.

Paper Details

Date Published: 21 February 2020
PDF: 5 pages
Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112282M (21 February 2020); doi: 10.1117/12.2547317
Show Author Affiliations
Yi Zhou, National Univ. of Ireland (Ireland)
Sergey Alexandrov, National Univ. of Ireland (Ireland)
Andrew Nolan, National Univ. of Ireland (Ireland)
Rajib Dey, National Univ. of Ireland (Ireland)
Nandan Das, National Univ. of Ireland (Ireland)
Kai Neuhaus, Compact Imaging Ireland Ltd. (Ireland)
Martin Leahy, National Univ. of Ireland (Ireland)


Published in SPIE Proceedings Vol. 11228:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV
Joseph A. Izatt; James G. Fujimoto, Editor(s)

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