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Proceedings Paper

Visible light optical coherence microscopy for quantitative imaging of human skin in vivo
Author(s): Shau Poh Chong; Zhen Yu Gordon Ko; Nanguang Chen
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Paper Abstract

Recent development of visible light Optical Coherence Microscopy (i.e. Optical Coherence Tomography employing high numerical aperture Objective) has pushed the axial/transverse resolution limit to < 2 μm within tissues. Here, a fiber-based visible light Fourier domain (FD) Optical Coherence Microscopy system is presented, employing a 10x water immersion objective to achieve higher transverse resolution and reduced specular reflection when imaging human skin in vivo, using ~ 1-2 mW of incident power. Though with limited penetration depth, we demonstrated its application for in vivo imaging of human skin, and further measured the thicknesses of epidermis and dermo-epidermal junction. Furthermore, the total attenuation coefficient of the skin tissues was also estimated across epidermis and dermis.

Paper Details

Date Published: 19 February 2020
PDF: 8 pages
Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 1121109 (19 February 2020); doi: 10.1117/12.2547149
Show Author Affiliations
Shau Poh Chong, National Univ. of Singapore (Singapore)
Zhen Yu Gordon Ko, National Univ. of Singapore (Singapore)
Nanguang Chen, National Univ. of Singapore (Singapore)

Published in SPIE Proceedings Vol. 11211:
Photonics in Dermatology and Plastic Surgery 2020
Bernard Choi; Haishan Zeng, Editor(s)

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