Share Email Print
cover

Proceedings Paper

Digital micromirror device based angle-multiplexed optical diffraction tomography for high throughput 3D imaging of cells
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

The development of high throughput three-dimensional (3D) microscopic imaging technique is important for studying cell physiology and early-stage disease diagnoses. Here we propose and demonstrate a digital micromirror device (DMD) based angle-multiplexed high-speed optical diffraction tomography (ODT) technique. Using this ODT technique, we have achieved 3D imaging of cells at over 600 tomogram/second speed, which is 10-100 times faster than current ODTbased 3D cell imaging techniques. We envision that this high-speed ODT system will enable many cutting-edge biomedical applications, such as capturing millisecond scale cell dynamics in 3D space and high throughput 3D imaging of large cell populations.

Paper Details

Date Published: 28 February 2020
PDF: 6 pages
Proc. SPIE 11294, Emerging Digital Micromirror Device Based Systems and Applications XII, 1129402 (28 February 2020); doi: 10.1117/12.2547017
Show Author Affiliations
Yanping He, The Chinese Univ. of Hong Kong (Hong Kong, China)
Yijin Wang, The Chinese Univ. of Hong Kong (Hong Kong, China)
Renjie Zhou, The Chinese Univ. of Hong Kong (Hong Kong, China)


Published in SPIE Proceedings Vol. 11294:
Emerging Digital Micromirror Device Based Systems and Applications XII
John Ehmke; Benjamin L. Lee, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray