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Proceedings Paper

Low-cost photoacoustic computed tomography system using light-emitting-diodes
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Paper Abstract

Photoacoustic computed tomography (PACT) has been widely explored for studying human diseases as well as response to therapies. Most PACT systems employ a large footprint, bulky, and high-cost lasers. Light emitting diodes (LEDs) based B-mode photoacoustic imaging systems have emerged as a low cost and compact alternative, offering a unique opportunity to expedite the widespread adoption of photoacoustic imaging in clinical and resource-poor settings. The high pulse repetition rate of LEDs facilitates signal-to-noise ratio improvements through averaging in spite of lower pulse energy. Here, we present the development of first low-cost LED-based PACT system that uses multiple LED arrays and a linear ultrasound transducer to generate three-dimensional structural, functional and molecular images of the object. Similar to OPO based lasers, our LED-PACT system allows for the multi-wavelength photoacoustic imaging vital for mapping functional and molecular information. Our experiments demonstrate that this study will enable clinical and pre-clinical applications such as imaging human arthritis and whole body mouse imaging.

Paper Details

Date Published: 17 February 2020
PDF: 8 pages
Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 1124058 (17 February 2020); doi: 10.1117/12.2546993
Show Author Affiliations
Sumit Agrawal, The Pennsylvania State Univ. (United States)
Xinyi Yang, The Pennsylvania State Univ. (United States)
Hussain Albahrani, The Pennsylvania State Univ. (United States)
Christopher Fadden, The Pennsylvania State Univ. (United States)
Ajay Dangi, The Pennsylvania State Univ. (United States)
Mithun Kuniyil Ajith Singh, Cyberdyne, Inc. (Netherlands)
Sri-Rajasekhar Kothapalli, The Pennsylvania State Univ. (United States)

Published in SPIE Proceedings Vol. 11240:
Photons Plus Ultrasound: Imaging and Sensing 2020
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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