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Proceedings Paper

Multiscale imaging of the ex vivo oral precancerous lesions with a custom developed swept-source optical coherence tomography/microscopy platform and a 1.7 µm wavelength-swept laser (Conference Presentation)

Paper Abstract

Oral cancer was ranked as the fifth most common cancers in both sexes in Taiwan in 2014. For patients diagnosed with the advanced or late stage of oral SCC, the five-year survival rate is reported to be ~ 33% suggesting the importance of the early detection of oral cancer. There have been various studies of investigating the clinical utility of OCT for the early detection of oral precancerous lesions with 1300 nm OCT technology. In this study, we have developed a long-wavelength, multiscale OCT imaging system enabling multiscale imaging of the ex vivo oral precancerous tissue with an increased imaging depth. Objectives with two different magnifications are mounted to a power turret, enabling seamless change of the OCT imaging resolution via the software control. OCT imaging over a variety of oral precancer pathologies will be demonstrated with above OCT system.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11217, Lasers in Dentistry XXVI, 112170C (9 March 2020); doi: 10.1117/12.2546988
Show Author Affiliations
Chuan-Bor Chueh, National Taiwan Univ. (Taiwan)
Ching-Yu Wang, National Taiwan Univ. (Taiwan)
Ting-Yen Tsai, National Taiwan Univ. (Taiwan)
Yin-Peng Huang, National Taiwan Univ. (Taiwan)
Teng-Chieh Chang, National Taiwan Univ. (Taiwan)
Ting-Hao Chen, National Taiwan Univ. (Taiwan)
You-Nan Tsai, National Taiwan Univ. (Taiwan)
Yi-Ping Hung, National Taiwan Univ. (Taiwan)
Hsiang-Chieh Lee, National Taiwan Univ. (Taiwan)

Published in SPIE Proceedings Vol. 11217:
Lasers in Dentistry XXVI
Peter Rechmann; Daniel Fried, Editor(s)

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