
Proceedings Paper
Cerebral hemodynamics measured with diffuse optical spectroscopies to elucidate mechanisms of cognitive dysfunction after mild traumatic brain injury (Conference Presentation)
Paper Abstract
Near infrared spectroscopy (NIRS) combined with diffuse correlation spectroscopy (DCS) enable non-invasive, bedside assessment of brain blood flow and metabolism. In numerous disease states (e.g., stroke, traumatic brain injury) these hemodynamic parameters are deranged, and these derangements have diagnostic and/or prognostic value. However, to best utilize NIRS/DCS data to guide patient care, we need a mechanistic understanding of the molecular changes underlying hemodynamic and metabolic dysfunction. Using a mouse model of repetitive mild traumatic brain injury, we present an example of how preclinical studies with NIRS/DCS can aid in the interpretation and utility of clinical NIRS/DCS datasets.
Paper Details
Date Published: 10 March 2020
PDF
Proc. SPIE 11253, Biomedical Applications of Light Scattering X, 1125308 (10 March 2020); doi: 10.1117/12.2546970
Published in SPIE Proceedings Vol. 11253:
Biomedical Applications of Light Scattering X
Adam Wax; Vadim Backman, Editor(s)
Proc. SPIE 11253, Biomedical Applications of Light Scattering X, 1125308 (10 March 2020); doi: 10.1117/12.2546970
Show Author Affiliations
Erin M. Buckley, Emory Univ. (United States)
Published in SPIE Proceedings Vol. 11253:
Biomedical Applications of Light Scattering X
Adam Wax; Vadim Backman, Editor(s)
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