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Proceedings Paper

Low-cost glucose biosensor fabricated by a photosensitive resin that features nanoparticles
Author(s): J. V. Guzmán; M. I. Saldana; A. A. Polokhin; A. A. Castillo; V. Guzman
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Paper Abstract

A low-cost biosensor for glucose analysis was designed, fabricated and characterized. It was fabricated by using a DLPdirect light processing, 3D printed technique. The operation principle for the electro-optic device is based on the total internal reflection. The photosensitive resin is considered that is doped with nanoparticles such as quantum dots and carbon nanotubes as a waveguide. By using DLP 3D printing technique the device was fabricated. The operation principle was based on the optical phase shift. The entire structure of the device features a Mach-Zehnder Interferometer (MZI) that was numerically analyzed in a commercial software featuring finite element. The biosensor works in the transmission scheme. Mach-Zehnder interferometer is composed of a waveguide that encompasses the resin doped with nanodots that linked both input and output signals. In contrast, one arm is kept isolated and the other arm exposed to the medium in order to obtain the phase change at the MZI output. A laser-diode of 980 nm was considered as the source. The optical array features a single-mode optic fiber and a bidirectional coupler. While tested, several glucose concentrations (from 0% to 3%) were provided in order to determine the relationship between the glucose concentration and the output signal in order to increase the sensitivity. The future possibility of the aforementioned structure describes the use of several materials for biological-related applications are also discussed.

Paper Details

Date Published: 21 February 2020
PDF: 5 pages
Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 112541C (21 February 2020); doi: 10.1117/12.2546938
Show Author Affiliations
J. V. Guzmán, Univ. Autónoma de Nuevo León (Mexico)
M. I. Saldana, Univ. Autónoma de Nuevo León (Mexico)
A. A. Polokhin, Univ. Autónoma de Nuevo León (Mexico)
A. A. Castillo, Univ. Autónoma de Nuevo León (Mexico)
V. Guzman, Univ. Autónoma de Nuevo León (Mexico)

Published in SPIE Proceedings Vol. 11254:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII
Dror Fixler; Ewa M. Goldys, Editor(s)

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