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Proceedings Paper

Mapping deep brain stimulation’s impact on cortical networks using high-density diffuse optical tomography (Conference Presentation)
Author(s): Arefeh Sherafati; Adam T. Eggebrecht; Tracy M. Burns-Yocum; Heather M. Lugar; Anagha Narayanan; Tasha Doty; Alexandra M. Svoboda; Mariel L. Schroeder; Abraham Z. Snyder; Mwiza Ushe; Joseph P. Culver; Tamara Hershey

Paper Abstract

Current gold standard neuroimaging tools lack either necessary temporal resolution (PET) or optimal safety due to contraindications (fMRI) for measuring the neural mechanisms underlying the effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson disease (PD). In this study, we validate the feasibility of High-Density Diffuse Optical Tomography (HD-DOT) for mapping the cortical activity of the PD patients with their STN DBS ON and OFF during auditory and visual tasks and during resting state.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11226, Neural Imaging and Sensing 2020, 112260A (9 March 2020); doi: 10.1117/12.2546903
Show Author Affiliations
Arefeh Sherafati, Washington Univ. School of Medicine in St. Louis (United States)
Adam T. Eggebrecht, Washington Univ. School of Medicine in St. Louis (United States)
Tracy M. Burns-Yocum, Indiana Univ. (United States)
Heather M. Lugar, Washington Univ. School of Medicine in St. Louis (United States)
Anagha Narayanan, Washington Univ. School of Medicine in St. Louis (United States)
Tasha Doty, Washington Univ. School of Medicine in St. Louis (United States)
Alexandra M. Svoboda, Washington Univ. School of Medicine in St. Louis (United States)
Mariel L. Schroeder, Washington Univ. School of Medicine in St. Louis (United States)
Abraham Z. Snyder, Washington Univ. School of Medicine in St. Louis (United States)
Mwiza Ushe, Washington Univ. School of Medicine in St. Louis (United States)
Joseph P. Culver, Washington Univ. School of Medicine in St. Louis (United States)
Tamara Hershey, Washington Univ. School of Medicine in St. Louis (United States)


Published in SPIE Proceedings Vol. 11226:
Neural Imaging and Sensing 2020
Qingming Luo; Jun Ding; Ling Fu, Editor(s)

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