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Proceedings Paper

Sensorless adaptive optics optical coherence tomographic angiography (OCTA) of the retinal plexuses (Conference Presentation)
Author(s): Acner Camino Benech; Pengxiao Zang; Yukun Guo; Ringo Ng; Joey Huang; Yali Jia; David Huang; Yifan Jian

Paper Abstract

In OCTA, resolution of retinal capillaries is limited by physical numerical aperture of human eye and the subject’s ocular aberrations. Adaptive optics OCTA has been demonstrated in instruments with large numerical aperture, originally designed for the visualization of retinal cells. In this work, we propose a high-speed, spectral domain sensorless adaptive optics OCTA instrument with a 3-mm beam to image retinal capillaries of all three retinal plexuses simultaneously, with high axial and lateral resolution. A novel and fast hill climbing algorithm was applied on the amplitude of six low-order Zernike modes to minimize ocular aberrations based on maximizing en face merit functions of the layer of interest computed in real time.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280V (9 March 2020); doi: 10.1117/12.2546884
Show Author Affiliations
Acner Camino Benech, Oregon Health & Science Univ. (United States)
Pengxiao Zang, Oregon Health & Science Univ. (United States)
Yukun Guo, Oregon Health & Science Univ. (United States)
Ringo Ng, Simon Fraser Univ. (Canada)
Joey Huang, Simon Fraser Univ. (Canada)
Yali Jia, Oregon Health & Science Univ. (United States)
David Huang, Oregon Health & Science Univ. (United States)
Yifan Jian, Oregon Health & Science Univ. (United States)


Published in SPIE Proceedings Vol. 11228:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV
Joseph A. Izatt; James G. Fujimoto, Editor(s)

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