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Proceedings Paper

Patterns of interaction of the cell membrane with a matrix of natural polymers and carbon nanotubes
Author(s): Olga E. Glukhova; Michael M. Slepchenkov
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Paper Abstract

In this work, we investigate in silico the patterns of the interaction of natural polymer matrices based on a network of single-walled carbon nanotubes (SWCNTs), albumin and collagen with the cell membrane. A layer of phospholipid molecules is considered as a cell membrane. The simulation is carried by means of the coarse-grained approach using the MARTINI force field. During the simulation of contact of the membrane with the matrix, the membrane moved to the matrix with an average blood flow velocity of 0.5 m/s, which simulates the collision of blood elements with the surface of the SWCNT-natural polymer matrix. It is established that during the interaction of natural polymer matrices with cell membranes, the matrices do no harm to the cell membrane.

Paper Details

Date Published: 21 February 2020
PDF: 5 pages
Proc. SPIE 11256, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XII, 112560Q (21 February 2020); doi: 10.1117/12.2546746
Show Author Affiliations
Olga E. Glukhova, Saratov State Univ. (Russian Federation)
I.M. Sechenov First Moscow State Medical Univ. (Russian Federation)
Michael M. Slepchenkov, Saratov State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 11256:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XII
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

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