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Proceedings Paper

Chromophore selective multi-wavelength photoacoustic remote sensing (Conference Presentation)

Paper Abstract

To assess cancer resection margins, post-operative histological diagnosis using hematoxylin and eosin (H&E) stained slides remains the gold standard due to the lack of effective intra-operative approaches. Wait times may be up to two weeks and subsequent treatments may be necessary. Therefore, we are motivated to introduce Chromophore Selective Multi-Wavelength Photoacoustic Remote Sensing, an all-optical, non-contact, reflection-mode, label-free approach to produce H&E-like images of human tissue. This work is a step towards in-situ imaging, rapid clinical assessment of tissue, and may permit future developments as a live intraoperative surgical microscope.

Paper Details

Date Published: 20 April 2020
Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112400H (20 April 2020); doi: 10.1117/12.2546721
Show Author Affiliations
Nicholas Pellegrino, Univ. of Waterloo (Canada)
Saad R. Abbasi, Univ. of Waterloo (Canada)
Kevan Bell, Univ. of Waterloo (Canada)
Deepak Dinakaran, illumiSonics Inc. (Canada)
Gilbert Bigras, Univ. of Alberta (Canada)
John R. Mackey, illumiSonics Inc. (Canada)
Paul Fieguth, Univ. of Waterloo (Canada)
Parsin Haji Reza, Univ. of Waterloo (Canada)

Published in SPIE Proceedings Vol. 11240:
Photons Plus Ultrasound: Imaging and Sensing 2020
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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