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Proceedings Paper

In vivo validation of OCT hemodynamic measurement techniques with two-photon microscopy (Conference Presentation)

Paper Abstract

Over the past decades, several techniques have been developed to measure cerebral hemodynamic parameters such as red blood cell velocity, flux and hematocrit using optical coherence tomography (OCT). Despite these advancements, two photon microscopy (TPM) remains the gold standard for functional cerebral hemodynamic imaging, though localized line-scan or bolus tracking. Here we developed an optical platform enabling concurrent imaging with OCT and TPM and perform co-localized and simultaneous velocimetric measurements with both modalities, with the aim of validating OCT velocimetric methods.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280Y (9 March 2020); doi: 10.1117/12.2546720
Show Author Affiliations
Paul J. Marchand, Polytechnique Montréal (Canada)
Xuecong Lu, Polytechnique Montréal (Canada)
Cong Zhang, Polytechnique Montréal (Canada)
Yuankang Lu, Polytechnique Montréal (Canada)
Frédéric Lesage, Polytechnique Montréal (Canada)


Published in SPIE Proceedings Vol. 11228:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV
Joseph A. Izatt; James G. Fujimoto, Editor(s)

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