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Proceedings Paper

Nanoplasmonic-enhanced cellular imaging (Conference Presentation)
Author(s): Frederic A. Banville; Julien Moreau; Jean-François Bryche; Michel Grandbois; Michael T. Canva; Paul G. Charette

Paper Abstract

We have demonstrated, numerically and experimentally, that optimized nanostructured plasmonics substrates can generate new hybrid plasmonic modes that possess the spectral dispersion of propagating plasmon but with a much lower propagating length. The imaging performances of these nanostructured SPR chips were recently assessed by studying cellular responses following biochemical stimulation, in particular by real-time monitoring of integrity changes in confluent endothelial cell layer. Improvement in spatial resolution has resulted in an increase in detection sensitivity to cellular activity, with no detectable disturbances in cellular behavior due to the presence of nanostructures.

Paper Details

Date Published: 10 March 2020
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Proc. SPIE 11257, Plasmonics in Biology and Medicine XVII, 1125704 (10 March 2020); doi: 10.1117/12.2546529
Show Author Affiliations
Frederic A. Banville, Lab. Nanotechnologies Nanosystemes, CNRS (Canada)
Univ. de Sherbrooke (Canada)
Julien Moreau, Institut d'Optique Graduate School (France)
Jean-François Bryche, Lab. Nanotechnologies Nanosystemes, CNRS (Canada)
Univ. de Sherbrooke (Canada)
Michel Grandbois, Lab. Nanotechnologies Nanosystemes, CNRS (Canada)
Univ. de Sherbrooke (Canada)
Michael T. Canva, Lab. Nanotechnologies Nanosystemes, CNRS (Canada)
Univ. de Sherbrooke (Canada)
Paul G. Charette, Lab. Nanotechnologies Nanosystemes, CNRS (Canada)
Univ. de Sherbrooke (Canada)


Published in SPIE Proceedings Vol. 11257:
Plasmonics in Biology and Medicine XVII
Tuan Vo-Dinh; Ho-Pui A. Ho; Krishanu Ray, Editor(s)

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