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Proceedings Paper

Co-registered ultrasound and acoustic-resolution photoacoustic endoscopy for rectal cancer imaging in a pilot patient study* (Conference Presentation)

Paper Abstract

Rectal adenocarcinoma is a common cancer in the United States. Current standard of care techniques (colonoscopy and MRI) have notable drawbacks and surgeons have aggressively put most patients into surgical intervention. Developing an efficient and sensitive method to evaluate rectal cancer is urgently needed. Here we have developed a new handheld co-registered ultrasound and acoustic-resolution photoacoustic endoscope (AR-PAE) to evaluate human rectal cancer in vivo. Normal rectal ultrasound images revealed typical layered structure, while photoacoustic images resolved rich vascular supply of submucosa. Our pilot patient data suggest that AR-PAE is effective to distinguish rectal cancer from normal rectum.

Paper Details

Date Published: 20 April 2020
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Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112401J (20 April 2020); doi: 10.1117/12.2546498
Show Author Affiliations
Xiandong Leng, Washington Univ. in St. Louis (United States)
William Chapman Jr., Washington Univ. School of Medicine in St. Louis (United States)
Hongbo Luo, Washington Univ. in St. Louis (United States)
Guang Yang, Washington Univ. in St. Louis (United States)
Matthew Mutch, Washington Univ. School of Medicine in St. Louis (United States)
Quing Zhu, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 11240:
Photons Plus Ultrasound: Imaging and Sensing 2020
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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