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Proceedings Paper

Monitoring changes in kidney optical properties during cold storage preservation with spatial frequency domain imaging (Conference Presentation)
Author(s): Rebecca A. Rowland; Adrien Ponticorvo; Alberto Jarrin Lopez; Shiri Li; Hirohito Ichii; Anthony J. Durkin

Paper Abstract

Delayed graft function occurs in 40% of kidney transplantation cases, and is not apparent until after surgery has concluded. To understand changes in donor kidney tissue before transplantation, spatial frequency domain imaging (SFDI) was used to measure absorption and reduced scattering coefficients in excised porcine kidneys as they underwent a standard period of cold ischemic time (CIT). SFDI indicated an increase in reduced scattering and absorption. The scattering b parameter increased until 24 hours, then returned towards baseline. These results suggest that continued investigation may lead to the development of a noninvasive assessment for graft viability.

Paper Details

Date Published: 6 March 2020
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Proc. SPIE 11212, Therapeutics and Diagnostics in Urology 2020, 1121209 (6 March 2020); doi: 10.1117/12.2546409
Show Author Affiliations
Rebecca A. Rowland, Beckman Laser Institute and Medical Clinic (United States)
Adrien Ponticorvo, Beckman Laser Institute and Medical Clinic (United States)
Alberto Jarrin Lopez, Univ. of California, Irvine Medical Ctr. (United States)
Shiri Li, Univ. of California, Irvine Medical Ctr. (United States)
Hirohito Ichii, Univ. of California, Irvine Medical Ctr. (United States)
Anthony J. Durkin, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 11212:
Therapeutics and Diagnostics in Urology 2020
Hyun Wook Kang, Editor(s)

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