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Proceedings Paper

Photonic force optical coherence elastography for spectroscopic microrheological quantification of hydrogel viscoelasticity (Conference Presentation)

Paper Abstract

Photonic force optical coherence elastography (PF-OCE) is a new approach for volumetric characterization of microscopic mechanical properties of soft materials. PF-OCE utilizes harmonically modulated optical radiation pressure to exert localized mechanical excitation on individual microbeads embedded in viscoelastic media. We present microrheological quantification of complex shear modulus in polyacrylamide gels with PF OCE. Spectroscopic measurements over a frequency range spanning 1 Hz to 7 kHz revealed rich frequency-dependent microstructural dynamics of entangled polymer networks across multiple microrheological regimes. PF-OCE provides an all-optical approach to quantitative three-dimensional mechanical microscopy and broadband spectroscopic microrheological studies of soft materials.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 1124203 (9 March 2020); doi: 10.1117/12.2546372
Show Author Affiliations
Nichaluk Leartprapun, Cornell Univ. (United States)
Yuechuan Lin, Cornell Univ. (United States)
Steven G. Adie, Cornell Univ. (United States)

Published in SPIE Proceedings Vol. 11242:
Optical Elastography and Tissue Biomechanics VII
Kirill V. Larin; Giuliano Scarcelli, Editor(s)

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