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Proceedings Paper

Comparing the efficacy of infrared diode and Ho:YAG lasers for infrared neural stimulation (Conference Presentation)

Paper Abstract

Infrared neural stimulation (INS) has the potential to serve as a spatially precise tool for neuroscientists and clinicians. Because of difficulties comparing various INS techniques in the current literature, we present a study comparing the stimulation threshold and transition rate to 100% activation probability for diode and Ho:YAG lasers. The stimulation threshold was lower for the Ho:YAG than the diode lasers across all examined spot sizes. The Ho:YAG also exhibited a nearly binary transition to 100% activation that can be mimicked with diode lasers by decreasing the pulse width. These results will help maximize the performance of laser diodes for INS.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11227, Optogenetics and Optical Manipulation 2020, 112270R (9 March 2020); doi: 10.1117/12.2546270
Show Author Affiliations
Graham A. Throckmorton, Vanderbilt Univ. (United States)
Wilson R. Adams, Vanderbilt Univ. (United States)
Zane C. Ricks, Vanderbilt Univ. (United States)
Jonathan M. Cayce, Vanderbilt Univ. (United States)
E. Duco Jansen, Vanderbilt Univ. (United States)
Anita Mahadevan-Jansen, Vanderbilt Univ. (United States)


Published in SPIE Proceedings Vol. 11227:
Optogenetics and Optical Manipulation 2020
Samarendra K. Mohanty; E. Duco Jansen; Anna W. Roe, Editor(s)

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