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Proceedings Paper

Universal and quantitative measure of colloidal stability of plasmonic nanoparticles via comprehensive stability parameter method
Author(s): Wei-Kuan Lin; Somin Eunice Lee
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Paper Abstract

Plasmonic nanoparticles are expected to impact various fields, such as chemical analysis, superresolution imaging, and therapeutics. However, since plasmonic nanoparticles are known to be prone to aggregation, widespread use of plasmonic nanoparticles is still limited. While many methods have been proposed to enhance colloidal stability, a universal method to comprehensively detect stability is still lacking. We present a new comprehensive stability parameter (CSP) as a robust and universal method to quantify stability. Unlike other methods, CSP utilizes the entire UV-Vis spectrum to evaluate the aggregation and to avoid potential biasing issues by only looking at a single parameter. We quantitatively analyzed the colloidal stability of plasmonic particles with different surface coatings using CSP. This work establishes a standardized quantification method which can be used in the future nanoparticle applications.

Paper Details

Date Published: 21 February 2020
PDF: 7 pages
Proc. SPIE 11255, Colloidal Nanoparticles for Biomedical Applications XV, 112550H (21 February 2020); doi: 10.1117/12.2546244
Show Author Affiliations
Wei-Kuan Lin, Univ. of Michigan (United States)
Somin Eunice Lee, Univ. of Michigan (United States)

Published in SPIE Proceedings Vol. 11255:
Colloidal Nanoparticles for Biomedical Applications XV
Marek Osiński; Antonios G. Kanaras, Editor(s)

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