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Proceedings Paper

Continuous-wave coherent Raman spectroscopy via plasmonic enhancement for picomolar detection (Conference Presentation)
Author(s): Yashar E. Monfared; Travis M. Shaffer; Sanjiv S. Gambhir; Kevin C. Hewitt

Paper Abstract

We report a successful combination of stimulated Raman spectroscopy (SRS) and surface-enhanced Raman scattering (SERS) using cw laser sources and gold/silica nanoparticles with embedded reporter molecules. We describe the preparation method for our gold/silica nanoparticles as well as the effect of probe wavelength, pump and probe power, polarization and sample concentration on the cwSESRS signal. Altogether, a stable 10-12 orders of magnitude enhancement in the stimulated Raman signal is achieved because of the amplification of both pump and probe beams, leading us to detect pico-molar nanoparticle concentrations. The coherent Raman spectra matches the incoherent conventional Raman spectra of the reporter molecules. Unlike conventional incoherent SERS, this approach offers several advantages including improved trace analyte detection, the low cost accessibility of cw sources, and a coherent stimulated signal of microwatt intensities for applications such as Molecular Holography.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11264, Nonlinear Frequency Generation and Conversion: Materials and Devices XIX, 112641G (9 March 2020); doi: 10.1117/12.2546204
Show Author Affiliations
Yashar E. Monfared, Dalhousie Univ. (Canada)
Travis M. Shaffer, Stanford Univ. (United States)
Sanjiv S. Gambhir, Stanford Univ. (United States)
Kevin C. Hewitt, Dalhousie Univ. (Canada)

Published in SPIE Proceedings Vol. 11264:
Nonlinear Frequency Generation and Conversion: Materials and Devices XIX
Peter G. Schunemann; Kenneth L. Schepler, Editor(s)

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