Share Email Print
cover

Proceedings Paper

Fast and sensitive delineation of brain tumor with clinically compatible moxifloxacin labeling and confocal microscopy (Conference Presentation)

Paper Abstract

Surgical resection is the primary treatment for malignant brain tumors. This procedure has a dilemma—aggressive surgical resection tends to extend patient survival; however, it also increases the risk of neurological deficiencies. Current medical imaging methods are not sensitive and their interpretation largely depend on surgeon’s impression. High-speed cellular imaging method by using clinically applicable moxifloxacin was demonstrated for fast and sensitive tumor-detection. The detailed cytoarchitecture of brain tumor mouse model and malignant human brain tumors was revealed. This study showed the potential and feasibility of moxifloxacin-based confocal microscopy as a surgery-guiding method for tumor removal.

Paper Details

Date Published: 9 March 2020
PDF
Proc. SPIE 11229, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII, 112291F (9 March 2020);
Show Author Affiliations
Seunghun Lee, Pohang Univ. of Science and Technology (Korea, Republic of)
Wonyeong Park, Pohang Univ. of Science and Technology (Korea, Republic of)
Seonghan Kim, Pohang Univ. of Science and Technology (Korea, Republic of)
Hoonchul Chang, Pohang Univ. of Science and Technology (Korea, Republic of)
Bumju Kim, Pohang Univ. of Science and Technology (Korea, Republic of)
Won Hyuk Jang, Pohang Univ. of Science and Technology (Korea, Republic of)
Younghoon Shin, Gwangju Institute of Science and Technology (Korea, Republic of)
Myoung Joon Kim, Lid Lab. (Korea, Republic of)
Euiheon Chung, Gwangju Institute of Science and Technology (Korea, Republic of)
Eui Hyun Kim, Yonsei Univ. College of Medicine (Korea, Republic of)
Kyung Hwa Lee, Chonnam National Univ. Medical School (Korea, Republic of)
Ki Hean Kim, Pohang Univ. of Science and Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 11229:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII
Anita Mahadevan-Jansen, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray