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Proceedings Paper

Separating scalp and brain layer hemodynamics on a single channel diffuse optical spectroscopy (Conference Presentation)

Paper Abstract

Functional near-infrared spectroscopy (fNIRS) has been gaining much attention in biophotonics fields because it provides brain activity based on monitoring of hemodynamic changes. Even though fNIRS has shown significant results in brain research, the question has been raised about the origin of hemodynamic changes, due to the uncertainty of the light path in the brain structure. The goal of this study is to separate the scalp and brain layer hemodynamic by developing diffuse reflectance spectroscopy based on two-layered photon diffusion reflectance equation. In order to validate our approach, the simulation experiments were carried out. During the experiment, various tissue reflectance spectra corresponding to various hemodynamic conditions of the superficial and brain layers were generated by simulation. The results show the potential of our approach that separating brain hemodynamics from tissue reflectance spectrums.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11216, Multiscale Imaging and Spectroscopy, 112160K (9 March 2020);
Show Author Affiliations
Sungchul Kim, Gwangju Institute of Science and Technology (Korea, Republic of)
Jae Gwan Kim, Gwangju Institute of Science and Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 11216:
Multiscale Imaging and Spectroscopy
Paul J. Campagnola; Kristen C. Maitland; Darren M. Roblyer, Editor(s)

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