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Proceedings Paper

Functional imaging of the retina with phase-sensitive full-field swept-source optical coherence tomography (Conference Presentation)
Author(s): Dierck Hillmann; Clara Pfäffle; Hendrik Spahr; Felix Hilge; Sazan Burhan; Katharina Gercke; Yoko Miura; Gereon M. Hüttmann

Paper Abstract

We demonstrate functional in vivo imaging of photoreceptor and neuronal layers within the living human retina by looking at the expansion of their optical path length. To this end, we use a special full-field swept-source optical coherence tomography system that acquires all lateral points in parallel, achieving a high-speed data acquisition with up to 200 volumes per second. A combination of computational motion and aberration correction with a suitable phase evaluation scheme yields minuscule changes after exposing the photoreceptors to a white light stimulus.

Paper Details

Date Published: 11 March 2020
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Proc. SPIE 11249, Quantitative Phase Imaging VI, 112490U (11 March 2020); doi: 10.1117/12.2545969
Show Author Affiliations
Dierck Hillmann, Thorlabs GmbH (Germany)
Univ. zu Lübeck (Germany)
Clara Pfäffle, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Hendrik Spahr, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Felix Hilge, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Sazan Burhan, Univ. zu Lübeck (Germany)
Katharina Gercke, Univ. zu Lübeck (Germany)
Yoko Miura, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Gereon M. Hüttmann, Univ. zu Lübeck (Germany)
Medizinisches Laserzentrum Lübeck GmbH (Germany)
Airway Research Ctr. North (ARCN), a Member of Deutsches Zentrum Für Lungenforschung (Germany)


Published in SPIE Proceedings Vol. 11249:
Quantitative Phase Imaging VI
Yang Liu; Gabriel Popescu; YongKeun Park, Editor(s)

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