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Proceedings Paper

Time-domain diffuse correlation spectroscopy of turbid media with mixed dynamics (Conference Presentation)

Paper Abstract

We apply time-domain diffuse correlation spectroscopy (TD DCS) to quantify dynamics in samples with mixed dynamics, containing both static and dynamic scatterers. We demonstrate that standard TD DCS processing is incapable to properly quantify dynamics at short source-detector distances due to the strong influence of the static component. To solve this problem, we introduce a novel model, which allows recovering the autocorrelation decay of the dynamic part properly. We then apply this novel approach in humans in vivo. We recovered the blood flow index of the leg muscle covered by the thin static turbid layer during the cuff occlusion challenge.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 1123906 (9 March 2020); doi: 10.1117/12.2545598
Show Author Affiliations
Dawid Borycki, Institute of Physical Chemistry (Poland)
Saeed Samaei, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)
Michal Kacprzak, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)
Piotr Sawosz, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)
Adam Liebert, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)


Published in SPIE Proceedings Vol. 11239:
Dynamics and Fluctuations in Biomedical Photonics XVII
Valery V. Tuchin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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